本实验室关于纤维素乳酸生产菌株与生物解毒真菌竞争关系的论文在Bioresources and Bioprocessing发表。本文的第一作者单位为华东理工大学。李治斌为第一作者，通讯作者为鲍杰，合作作者包括张凌霄（华东理工大学）、何妮玲（华东理工大学）、张斌（华东理工大学）。

Zhibin Li¹, Lingxiao Zhang¹, Niling He¹, Bin Zhang¹, Jie Bao^1*. Competition between biodetoxification fungus and lactic acid bacterium in the biorefinery processing chain for production of cellulosic L-lactic acid. Bioresources and Bioprocessing (2024) 11:54.

Abstract Biodetoxification fungus selectively degrades toxic inhibitors generated from pretreatment of lignocellulose without consuming fermentable sugars. However, one barrier for practical application is the sustained cell viability in the consequent fermentation step to compete the fermentable sugars with fermenting strains, resulting in sugar loss and reduced target product yield. This study investigated the competitive growth property between the biodetoxification fungus Paecilomyces variotii FN89 and the L-lactic acid bacterium Pediococcus acidilactici ZY271 under varying temperature and lactic acid osmatic stress. The results show that the L-lactic acid bacterium Ped. acidilactici ZY271 showed less thermotolerance to Pae. variotii FN89 at high temperature of 45 °C to 50 °C in both synthetic medium and wheat straw hydrolysate. In the higher temperature environment, the growth of the biodetoxification strian failed to compete with the lactic acid fermentation strain and was quickly eliminated from the fermentation system. The high temperature fermentation facilitated a fast transition from the detoxification stage to the fermentation stage for higher production of L-lactic acid.

Keywords Lignocellulose, Biodetoxification, High temperature, L-lactic acid fermentation, Paecilomyces Variotii FN89, Pediococcus acidilactici ZY271