第466次 SKLBE学术论坛(Prof. Joerg C. Tiller)

题目：Smart and Bioactive Polymer Systems: Antimicrobial polymers and surfaces, bio-mineralized hydrogels, and smart polymer networks

报告人：Prof. Joerg C. Tiller

时间：2019-5-15  10:00-11:30

地点：实验18楼315室

主持人： 刘润辉教授

Biography

1995                Dipl.-Chem                            Friedrich-Schiller-Universität (FSU), Jena

1999                Dr. rer. nat.                             FSU

1999-2001      Postdoc                                  Massachusetts Institute of Technology

2002-2007      Group Leader                         University of Freiburg

2007-              Professor                                Technische Universität Dortmund

Awards

2002-2007      Emmy-Noether-Programm of the DFG

2003                Georg Manecke Award of the GDCh

2006                Chemistry Award of the Academy of Science of Göttingen

2007                Chemiedozentenstipendium of Fonds of the Chemical Industry

2010-              Editorial Board Member of Scientific Reports (Nature Publishing Group)

Abstract

Polymers offer the opportunity to insert functions into complex systems. This presentation will cover our recent advances in antimicrobial polymers and surfaces, enzyme-induced mineralizable hydrogel, and shape memory, smart and predictive materials.

One approach towards antimicrobial polymers is the opportunity of controlling a biocidal end group on a neutral polymer, e.g., poly (2-oxazoline) via the group at the other end, the satellite group. This effect can be used to control the antimicrobial activity of the polymer over several orders of magnitude. ^[1] The satellite group was transferred to hydrophilic antimicrobial polymers, which were designed to be degradable and lose their activity within minutes upon partial degradation. Using antimicrobial polymers to design antimicrobial surfaces will be discussed, particularly with respect to the mechanisms of contact-active surfaces. The novel mechanism of the phospholipid sponge effect has been applied to silicones, which results in the first lotus-effect, antimicrobial surface. ^[2]

Further, bioactive polymer networks with embedded, highly activated enzymes will be presented. Such systems can be mineralized using enzymatic reactions. This leads to ultra-stiff and tough organic/inorganic hydrogel double networks, where the inorganic phase is fully percolated, improving the stiffness of the materials by several orders of magnitude. ^[3]

Another class of smart materials with shape memory properties, environmental memory and self-healing properties will be shown. Such polymer networks are based on critically cross-linked high polymers, e.g., natural rubber or syndiotactic polypropylene (sPP), which allows large elongations and formation of crystals, which stabilize the material upon strain.^[4] The programmed materials react to environmental stimuli, such as temperature, solvents or stress. In case of sPP, the cross-linked materials even reacts to heating rates, which makes this system the first predictive material.^[5]

References

[1]     C. Krumm, S. Harmuth, M. Hijazi, B. Neugebauer, A. L. Kampmann, H. Geltenpoth, A. Sickmann, J. C. Tiller, Angewandte Chemie - International Edition 2014, 53, 3830-3834.

[2]     N. Rauner, C. Mueller, S. Ring, S. Boehle, A. Strassburg, C. Schoeneweiss, M. Wasner, J. C. Tiller,Advanced Functional Materials 2018, 28.

[3]     N. Rauner, M. Meuris, M. Zoric, J. C. Tiller, Nature 2017, 543, 407-410.

[4]     F. Katzenberg, B. Heuwers, J. C. Tiller, Advanced Materials 2011, 23, 1909-1911.

[5]     R. Hoeher, T. Raidt, F. Katzenberg, J. C. Tiller, ACS Applied Materials and Interfaces 2016, 8, 13684-13687.

祝好！