李忠

发布时间：2018-09-04 18:09:00

李忠

华东理工大学特聘教授、博士生导师、上海市化学生物学重点实验室主任、药物化工研究所所长。

主要从事绿色农药创制研究，创制品种“哌虫啶”、“环氧虫啶”相继获得国家农药登记许可；获第四届中国农药行业技术创新优秀奖（唯一个人奖项）、第八届中国农药工业协会农药创新贡献奖技术创新奖二等奖、第九届中国农药工业协会农药创新贡献奖技术创新奖一等奖等。入选或获得中组部“”、科技部中青年科技创新领军人才、教育部新世纪优秀人才、上海市领军人才、上海市优秀学科带头人、上海市曙光学者等人才项目或称号；主持完成国家“863”课题、国家“973”子课题、科技支撑子课题、国家自然科学基金、上海市科委重点项目等数十项国家及省部级重要科研项目。兼任中国化工学会农药专业委员会委员、上海市化学化工学会农药专业委员会副会长、《中国化学快报》编委、《农药学学报》编委等，曾任“863”现代农业领域重大项目总体专家。在J. Agric. Food Chem., Insect Biochem. Mol. Biol., Environ. Sci. Technol.等农药研究领域具有重要影响的国际期刊发表SCI论文100余篇。申请发明专利八十余项，其中PCT专利14项、国外专利38项；获得中国发明专利授权20余项，外国发明专利授权15项(美国3项)。

科研项目

1. 国家自然科学基金面上项目，21472046，杂环烯胺合成方法学研究及其在杀虫剂创制中的应用，2015.01-2018.12，80万元，正在进行，主持
2. （科技创新领军人才），2014年
3. 科技部中青年科技创新领军人才，2013年，农药学
4. 863课题，2011AA10A207，基于靶标的新型化学农药设计合成、优化与产品创制，2011.01-2015.12，877万元，已结题，主持

近期论文

1. Yin Xu, Fukai Wang, Jilin Li, Xusheng Shao, Xiaoyong, Xu, Zhong Li*. Synthesis of novel imidazopyrrolo-fused isoxazole derivatives through acid-mediated intramolecular 1,3-dipolar cycloaddition. Synlett 2016, 27, 1397-1402

2. Hui Zeng, Pengtao Yuan, Fukai Wang, Xiaoyong Xu, Xusheng Shao, Zhong Li*. A novel and selective synthetic approach for the access of pyrrolo[1,2-a] imidazol-7-one or pyrrol-3-one. Tetrahedron Lett. 2016, 57, 4031–4035

3. Haibo Bao, Xusheng Shao, Yixi Zhang, Yayun Deng, Xiaoyong Xu, Zewen Liu, Zhong Li*. Specific Synergist for Neonicotinoid Insecticides: IPPA08, a cis-Neonicotinoid Compound with a Unique Oxabridged Substructure. J. Agric. Food Chem. 2016, 64, 5148–5155.

4. Li Han, Yian Feng, Ming Luo, Zihao Yuan, Xusheng Shao, Xiaoyong Xu, Zhong Li*, 2,2,2-Trifluoroethanol activated one-pot Mannich-like reaction of b-nitroenamines, secondary amines, and aromatic aldehydes. Tetrahedron Lett. 2016, 57, 2727–2731.

5. Ye Liu, Chao Lei, Xiaoyong Xu, Xusheng Shao, Zhong Li*. Design, synthesis and insecticidal activity of biphenyl-diamide derivatives, Chin. Chem. Lett. 2016, 27, 321-324.

6. Jiling Li, Dang Wu, Xiaoyong Xu, Jin Huang, Xusheng Shao and Zhong Li*. Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1, 3-benzoazole derivatives bearing amide units. Bioorg. Med. Chem. Lett. 2016, 26, 3064-3066.

7. Yefeng Fan, Wenwen Zhang, Xusheng Shao, Zhiping Xu, Xiaoyong Xu, Zhong Li*. Facile three-component synthesis and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine derivatives. Chin. Chem. Lett. 2015, 26 : 1-5.

8. Yefeng Fan, Song Liu, Nanyang Chen, Xusheng Shao, Xiaoyong Xu, Zhong Li*. Oxidation Strategy for the Synthesis of Regioisomeric Spiroisobenzofuranopyrroles: Facile Entries to Spiro[isobenzofuran-1,2′-pyrrole] and Spiro[isobenzofuran-1,3′-pyrrole] Derivatives. Synlett. 2015, 26, 393-403.

9. Yanpeng Lou, Gang Zhao*, Zhong Li*. Enantioselective direct mannich reactions of cyclic β-ketoesters catalyzed by chiral phosphine via a novel dual-reagent catalysis. Org. Lett. 2015, 17, 688-691.

10. Baoyan Zhang, Zhiping Xu*, Yixi Zhang, Xusheng Shao, Xiaoyong Xu, Jiagao Cheng, Zhong Li*. Fipronil induces apoptosis through caspase-dependent mitochondrial pathways in Drosophila S2 cells. Pestic. Biochem. Physiol. 2015, 119, 81-89.

11. Xuanqi Liu, Xiaoyong Xu, Chao Li, Hanxue Zhang, Qiuguo Fu, Xusheng Shao, Qingfu Ye*, Zhong Li*. Degradation of chiral neonicotinoid insecticide cycloxaprid in flooded and anoxic soil. Chemosphere, 2015, 119, 334-341.

12. Xuanqi Liu, Xiaoyong Xu, Qingfu Ye*, Zhong Li*. Bioavailability and release of nonextractable (bound) residues of chiral cycloxaprid using geophagous earthworm metaphire guillelmi in rice paddy soil. Sci. Total Environ. 2015, 526: 243-250.

13. Xuanqi Liu, Xiaoyong Xu, Chao Li, Hanxue Zhang, Qiuguo Fu, Xusheng Shao, Qingfu Ye*, Zhong Li*. Assessment of the Enviromental Fate of Cycloxaprid in Flooded and Anaerobic Soils by Radioisotopic Tracing. Sci. Total Environ.. 2016, 543: 116-122.

14. Renbo Xu, Rui Xia, Ming Luo, Xiaoyong Xu*, Jiagao Cheng, Xusheng Shao, Zhong Li*. Design, Synthesis, Crystal Structures, and Insecticidal Activities of Eight-Membered Azabridge Neonicotinoid Analogues. J. Agric. Food Chem., 2014, 62(2), 381–390

联系方式

地址：上海市梅陇路130号实验18楼1420室
邮编：200237
电话：021-64253984
Email：lizhong@ecust.edu.cn