CAO Xue-Jun (Prof. & Ph.D)

Education

Ph.D. (Sept., 1993-Jul., 1996)

University: East China Univ. Sci & Tech, Shanghai,China.

Specialty: Bioseparation

Dissertation: Purification of Urokinase by Affinity Cross-flow Filtration and Affinity Chromatography 

Master (Sept., 1990- Jul., 1993)

University: East China Univ. Sci. & Tech,Shanghai,China.

Specialty: Enzyme Reaction in Aqueous Two-phase Systems

Dissertation: Penicillin Bioconversion in Aqueous Tow-phase Systems by Recombinant Escherichia Coli with Intracellular Penicillin Acylase

College student (Sept., 1979-Jul., 1982)

College: Kaifeng Medical College (present Henan University), Henan Province, China.

Major in: Pharmacy

Research and Industrial Experience

Postdoc (Jan., 2000~Feb., 2002)

University: Depart.Biol. Eng. Inha University,South Korea

Project: Separation of Lactic Acid Coupled with Fermentation

       Separation of EPA and DHA from fish oil using 13X molecular sieve modified under supercritical condition

Professor (Jul., 2004-present)

University: State Key Lab of BioreactorEng., Dept. Biochem.Eng., East China Univ. Sci. & Tech.

Research areas

1.  Purification of Recombinant Protein and Natural active components

2.  Recycling Aqueous Two-phase Systems used for Extraction and Enzyme Catalytic Reactions

3.  Smart bioseparation copolymer

Teaching Experience

Teaching courses:

1 Bioseparation Engineering (Master students)

2 Bioseparation Engineering (Bachelor students, English-Chinese

bilanguage teaching)

Publications

1.    Huiyun Hou, Xuejun Cao* , pH recycling aqueous two-phase systems applied in extraction of Maitake β-Glucan and mechanism analysis using Low-Field Nuclear Magnetic Resonance，Journal of Chromatography A，2015，DOI: 10.1016/j.chroma.2015.05.076.

2.    Juan Xu, Xuejun Cao*, Characterization and mechanism of MoS2/CdS composite photocatalyst used for hydrogen production from water splitting under visible light，Chemical Engineering Journal，2015 , 260：642-648.

3.    Daisong Hou, Xuejun Cao?，Synthesis of two thermo-responsive copolymers forming recyclableaqueous two-phase systems and its application in cefprozil partition，Journal of Chromatography A，2014，1349 30–36

4.    Chaohui Zhu and Xuejun Cao*, Synthesis of Cefprozil Using Penicillin G Acylase in Recyclable Aqueous Two-phase Systems, Biotechnology and Bioprocess Engineering , 2014,19: 844-850.

5.    Xiaolei Ma, Xuejun Cao*, Separation of ursodeoxycholic acid by silylation crystallization, Bioresources and Bioprocessing, 2014, 1:5.

6.    Zhaoyang Ding, Sipeng Li, Xuejun  Cao*, Separation of lysozyme from salted duck egg white by affinity precipitation using pH-responsive polymer with an L-thyroxin ligand,Separation and Purification Technology, 2014,138 :153–160.

7.    Bo Yan, Xuejun Cao*, Phase diagram of novel recycling aqueous two-phase systems composed of two pH-response polymers: Experiment and modeling, Fluid Phase Equilibria, 2014, 364: 42–47.

8.    Jingjing Liu，Xuejun Cao*, Biodegradation of Cellulose by β-glucosidase and Cellulase Immobilized on a pH-responsive Copolymer, Biotechnology and Bioprocess Engineering,  2014, 19: 829-837

9.    Daisong Hou, Yanjie Li, Xuejun Cao*. Synthesis of two thermo-sensitive copolymers forming aqueous two-phase systems. Separation and Purification Technology, 2014,122 :217–224.

10. Xiangxi Yuan, Xiaolei Ma, and Xuejun Cao*, Preparation of ursodeoxycholic acid by direct electro-reduction of 7-ketolithocholic acid, Korean J. Chem. Eng., 2014, 31(7):1276-1280.

11. Tingting Yu, Xuejun Cao*, Effect of chaotropes on lipase back extraction recovery in the process of reverse micellar extraction, Applied Biochemistry and Biotechnology, 2014, 172(6):3287-3296.

12. Zhaoyang Ding, Kai Zheng, and Xuejun Cao* , Lipase Purification by Affinity Precipitation with a Thermo-responsive Polymer Immobilized Cibacron Blue F3GA Ligand, Biotechnology and Bioprocess Engineering, 2014, 19: 892-899.

13. Shutao Li，Xuejun Cao*,Enzymatic synthesis of Cephalexin in recyclable aqueous two-phase systems composed by two pH responsive polymers, Biochemical Engineering Journal, 2014, 90:301–306.

14. Daisong Hou, Xuejun Cao*，Synthesis of two thermo-responsive copolymers forming recyclableaqueous two-phase systems and its application in cefprozil partition，Journal of Chromatography A, 2014, 1349:30-36

15. Zhaoyang Ding, Lin Kang, Xuejun Cao* Application of docking methods for metal chelate affinity precipitation of endo-glucanase using pH-response polymer, Colloids and Surfaces B: Biointerfaces, 2014,113: 412–420.

16. Songli Li, Xuejun Cao*, Extraction of tea polysaccharides (TPS) using anionic reverse micellar system, Separation and Purification Technology , 2014, 122 306–314

17. Zhaoyang Ding and Xuejun Cao*，Affinity precipitation of human serum albuminusing a thermo-response polymer with an L-thyroxin ligand, BMC Biotechnology， 2013, 13:109

18. Jingjing Liu, Xuejun Cao*,Biodegradation of microcrystalline cellulose in pH–pH recyclable aqueous two-phase systems with water-soluble immobilized cellulose, Biochemical Engineering Journal, 2013, 79:136-143

19. Junfen Wan, Qingxi Li, Feng Zhou, Jingjing Liu, Xuejun Cao* ,Influence of chaotropes on recovery of trypsin and micellar sizes during reverse micelle extraction, Separation and Purification Technology, 2013, 116:307–31

20. He Tian, Hongbin Zhao, Xuejun Cao * Catalytic transfer hydrogenation of 7-ketolithocholic acid to ursodeoxycholic acid with Raney nickel, Journal of Industrial and Engineering Chemistry,2013,19: 606-613

21. Jingjing Liu, Xuejun Cao*，Biodegradation of cellulose in novel recyclable aqueous two-phase systems withwater-soluble immobilized cellulose, Process Biochemistry, 2012, 47: 1998–2004

22. Zhaoyang Ding, Xuejun Cao*, Affinity precipitation of cellulase using pH-response polymer with Cibacron Blue F3GA, Separation and Purification Technology, 2013，102：136–141

23. Bo Yan.  Xuejun Cao*， Preparation of aqueous two-phase systems composed of two pH-response polymers for liquid-liquid extraction of demeclocycline，Journal of Chromatography A, 2012,1245:39- 45

24. Wenjuan Liang, Xuejun Cao*, Preparation of a pH-sensitive polyacrylate amphiphilic copolymer and its application in cellulase immobilization, Bioresource Technology ,2012, 116:140-146

25. Yun-Xian Wang, Xue-Jun Cao *, Extracting keratin from chicken feathers by using a hydrophobic ionic liquid, Process Biochemistry, 2012, 47: 896–899

26. Junfen Wan,  Jiemin He,  Xuejun Cao*, A Novel Process for Preparing Pure Chenodeoxycholic Acid from Poultry Bile, J. Ind. Eng. Chem, 2012, 18: 65-71

27. Bo Zhou,Junfen Wan,Jinzhi Wang, Xuejun Cao*, Effect of chaotropes in reverse micellar extraction of kallikrein, Process Biochemistry, 2012, 47:229–233

28. Zhihua Jia, Xiaoli Zhang*, Xuejun Cao*, Jiandang Liu, Baofu Qin, Production of lovastatin by a self-resistant mutant of Aspergillus terreus, Ann Microbiol ,2011, 61:615–621

29. Yingying Wang, Xuejun Cao*,  Enzymatic synthesis of fatty acid ethyl esters by utilizing camellia oil soapstocks and diethyl carbonate, Bioresource Technology, 2011,102:10173–10179

30. Li Hui, Cao Xuejun*, Bioconversion of Cephalosporin-G to 7-ADCA in a pH-thermo       sensitive Recycling Aqueous Two-Phase Systems, Process Biochemistry, 2011， 46： 1753–1758

31. Baojun Yang and Xuejun CAO*, Synthesis the artemisinin-imprinting polymers on silica surface and its adsorption behavior in supercritical CO₂ fluid, AIChE J, 2011, 57(12):3512-3521

32. Xiao-Yan Gong, Xue-Jun Cao*, Preparation of molecularly imprinted polymers for artemisinin based on the surfaces of silica gel , Journal of Biotechnology, 2011,153:  8–14

33. Junfen Wan, Xuejun Cao*, Wei Wang,  Biao Ning, Xian Li,Partition of Several Model Bioproducts in recycling aqueous two-phase systems with pH/light responsive copolymers, Separation and Purification Technology , 2010,76:104–109

34. Siliang Zhang, Xuejun Cao, Ju Chu, Jiangchao Qian, and Yingping Zhuang, Bioreactors and Bioseparation, Adv Biochem Engin/Biotechnol, 2010,122: 105–150

35. Shu Miao, Jinpeng Chen, Xuejun Cao* Preparation of a novel hermo-sensitive copolymer forming recyclable aqueous two-phase systems and its application in bioconversion of Penicillin G, Separation and Purification Technology,2010, 75: 156–164

36. Yanjie Li, Xuejun Cao*, Prediction of phase diagrams for new pH-thermo sensitive recycling aqueous two-phase systems, Fluid Phase Equilibria, 2010, 298:206–211

37. Jinpeng Chen, Shu Miao , Junfen Wan, Jinan Xia, Xuejun Cao*, Synthesis and Initial Application of Two Light-Sensitive Copolymers Forming Recyclable Aqueous Two-Phase Systems, Process Biochemistry, 2010, 45:1928–1936

38.  Hongbin Zhao, He Tian, Yonghong Jin, Xuejun Cao*, Synthesis of 7-ketolithocholic   acid via indirect electrooxidation of chenodeoxycholic acid, J Appl. Electrochem, 2010),40:1307–1316

39.  LIANG Shuang, WAN Junfen*, ZHU Jianliang,CAO Xuejun*, Effects of porogens on the morphology and enantioselectivity of core-shell molecularly imprinted polymers with ursodeoxycholic acid, Separation and Purification Technology, 2010, 72: 208–216

40.  ZHOU Libo, WAN Junfen* ,CAO Xuejun*, Synthesis of thermo-sensitive copolymer with affinity butyl ligand and its application in lipase purification, Journal of Chromatography B, 2010, 878 : 1025–1030

41.   Song Qingrong, Zhu Jianliang, Wan Junfen,Cao Xuejun*, Measurement and modelling of epigallocatechin gallate solubility in supercritical carbon dioxide fluid with ethanol  cosolvent, Journal of Chemical Engineering Data, 2010, 55, 3946–3951

42.   Xian Li, Junfen Wan, Xuejun Cao*, Preliminary application of light-pH sensitive recycling aqueous two-phase systems to purification of lipase, Process Biochemistry, 2010，45：598–601

43.   Zhihua Jia,  Xiaoli Zhang,  Yaling Zhao, Xuejun Cao*, Effects of divalent metal cations on lovastatin biosynthesis from Aspergillus terreus in chemically defined medium, World J Microbiol Biotechnol 2009,25:1235–1241

44.   Zhihua Jia,1 Xiaoli Zhang,2* and Xuejun Cao*, Effects of carbon sources on fungal morphology and lovastatin biosynthesis by submerged cultivation of Aspergillus terreus, Asia-Pac. J. Chem. Eng. 2009;,4: 672–677

45.   Zhihua Jia  Xiaoli Zhang  Yaling Zhao*, Xuejun Cao*, Enhancement of Lovastatin Production by Supplementing Polyketide Antibiotics to the Submerged Culture of Aspergillus terreus，Appl Biochem Biotechnol，DOI 10.1007/s12010-009-8762-1

46.   Haixia Wang, JunfenWan, Xuejun Cao*，Preparation of a pH-sensitive affinity precipitation polymer and its application in purification of trypsin， Separation and  Purification Technology, 2009,68:172–177

47.  Xiao-Yan Gong, Xue-Jun Cao*, Measurement and correlation of solubility of  artemisinin in supercritical carbon dioxide, Fluid Phase Equilibria 2009,:284 26–30

48.  NING Biao  WAN Junfen  CAO Xuejun*  Preparation and recycling of aqueous                          two-phase systems with pH-sensitive amphiphilic terpolymer PADB, Biotechnology       Progress, 2009, 25(3):820-824 

49.  SHAO  Zhihua,  KONG  Fanqi,CAO Xuejun*, Phase Diagram Prediction of  Recycling Aqueous Two-Phase Systems formed by a Light-sensitive Copolymer and Dextran, Korea Journal of Chemical Engineering, 2009,26(1): 147-152

50.  WANG Wei, WAN Junfen, NING Biao,  XIA  Jinan,  CAO Xuejun*, Preparation of a Novel Light-Sensitive Copolymer and its Application in Recycling Aqueous Two-Phase Systems , Journal of Chromatography A，2008, 1205 (2008) 171–176

51.  Ziyun Xu, Junfen Wan, Shuang Liang and Xuejun Cao*, Separation of Ursodeoxycholic acid from its isomeric mixture using core-shell molecular imprinting polymer, Biochemical Engineering Journal, 2008. 41:280–287

52.  Wei QIN, Xue-Jun CAO*, Synthesis of a Novel pH-Sensitive Methacrylate Amphiphilic Polymer and Its Primary Application in Aqueous Two-phase Systems, Appl Biochem Biotechnol, 2008,150:171–183

53.  SHAO Zhihua  CAO Xuejun*, Prediction of BSA Partitioning in Recycling Aqueous Two Phase Systems composed of P_NBC-Dextran with Light-sensitive Polymer, Journal of Chemical Engineering Data, 2008, 53 (12), 2755-2757

54.  HAO Liu-Ping,CAO Xue-Jun*  HUR Byung-Ki, Separation of Single Component of EPA and DHA from Fish Oil Using Silver Ion Modified Molecular Sieve 13X under Supercritical Condition, J. Ind. Eng. Chem ,2008，14：639-643

55.  WEN Wen, WAN Junfen,CAO Xuejun^*, XIA Jinan, Preparation of a light-sensitive and reversible dissolution copolymer and its application in lysozyme purification, Biotechnology Progress, 2007 ，23：1124-1129

56.  Lin-Jie Chen, Xue-Jun Cao*，Avoiding Inactivation of Proteins in the process of  AOT/Isooctane Reverse Micellar Extraction，Journal of Chemical Engineering of Japan, 2007,40(6):511-515

57.  Kong Fan-Qi,Cao Xue Jun*, Xia Jinan, Synthesis and Application of a Light-sensitive Polymer Forming Aqueous Two-phase Systems, J. Ind. Eng. Chem. 2007, 13（3）424-428.

58.  Shen Li-Li;Cao Xuejun*, Synthesis of Thermo-sensitive Polyacrylamide Derivatives for Affinity Precipitation and its Application in Purification of Lysozyme, Biochen. Eng. J. 2007.33:66–71.

59.  Xuejun Cao and Byung-Ki Hur, Separation of EPA and DHA from Fish Oil Using Modified Zeolite 13X and Supercitical CO2, J. Ind. Eng. Chem., 2005, 11(5):762-768

60.  Cao Xuejun, Zhu Jianhang,  Wei Dongzhi and Byung Ki Hur, Cephalexin biosysthesis in PEG400-ammoniumsulfate and PEG400-magnisum sulfate aqueous two-phase systems, J. Microb.& Biotech., 2004, 14（1）：62-67.

61.  Cao Xue-jun, Wu Xing-yan, Luis J.P. Fonseca, Joaquim M.S. Cabral and Joao Carlos Marcos, Production of 6-aminopenicillanic acid in aqueous two-phase systems by recombinant Escherichia coli with intracellular penicillin acylase, Biotechnology Letters，2004, 26:97-101.

62.  Xuejun Cao, Jianhua Zhou, Zhenhui Huang, Xingyan Wu and Byung Ki Hur，  Preparation of high purity urokinase using single step hydrophobic interaction chromatography with p-aminobenzamidine ligand, J. Microb.& Biotech., 2002, 12(2):196-203 .

63.   Xuejun Cao,  Hyun Shik Yun  and  Yoon -Mo Koo， Recovery of L (+) Lactic Acid  by Anion Exchange Resin Amberlite IRA-400，Biochem. Eng. J.，2002，3592:1–8

64.  Cao Xuejun,  Zhu Jianhang,  Wei Dongzhi  and Byung Ki Hur，Partition improvement of cephalexin and 7-aminodeacetoxicephalospronic acid in aqueous two-phase systems for cephalexin synthesis,  J. Ind. & Eng., Chem., 2002, 8(3):203-211. .

65.  Xuejun  Cao,  Ho-Joon Lee, Hyun Shik Yun  and  Yoon -Mo Koo, Crystallization and Dissolution Behavior of L (+) Calcium and Zinc Lactate in Ethanol-Water Solvent,  Korea  J. Chem. Eng, 2002:19(2):301-304  

66.  Zhu Jianhang  Wei Dongzhi andCao Xuejun,  Effects of Hydrophobicity of Ethylene      oxide-Propylene oxide copolymers on Phase Diagrams of Aqueous Two-phase Systems and Partition Behaviors of Cephalexin and 7-aminodeacetoxicephalosporanic Acid, Chinese  J. Chem. Eng., 2002,(2):240-243.

67.  Xuejun Cao, XingYan Wu, Tong Wu,  Keming Jin and Byung Ki Hur， Concentration of 6-Aminopenicillanic Acid from Penicillin Bioconversion Solution and Its Mother Liquor by Nanofiltration Membrane, Biotech. And Bioproc. Eng., 2001, 6:200-204 .

68.  Xuejun Cao, Ho-Joon  Lee, Hyun Shik Yun and Yoon -Mo Koo， the Solubility of Calcium and Zinc Lactate in Water and Water–ethanol Mixture，Korea J. Chem. Eng., 2001, 18(1): 133-135.

69.  Jian-Hang Zhu, Dong-Zhi Wei, Xue-Jun Cao, Ye-Qing Liu and Zhong-Yi Yuan, Partitioning behavior of cephalexin and 7-aminodeacetoxicephalosporanic acid in PEG/ammonium sulfate aqueous two-phase systems,  J. Chem. Tech. and Biotech. 2001, 76:1194-1200..

70.  Dong-Zhi Wei, Jian-Hang Zhu and Xue-Jun Cao, High performance liquid Chromatographic Determination in the Enzyme Synthesis Process of Cephalexin, Internal Journal of Bio-Chromatography, 2001, 6:245-254.

71.  Dong-Zhi Wei， Jian-Hang Zhu, Xue-Jun Cao，Enzymatic synthesis of cephalexin in aqueous two-phase systems, Biochem. Eng. J., 2002, 3599:1-5.

72.  Meng Tang , Xuejun Cao, Zuozhen Liu, Xingyan Wu and Gance Dai, Synthesis of Glycidyl Methacrylate-Based Matrix and Its Application in Affinity Chromatography of Urokinase, Proc.  Biochem., 1999,34:857-862.

73.  Cao, X.J, Zhu, J.W., Wang, D.W., Wu, X.Y., and Dai,G.C., Affinty chromatography  purification of urokinase  with epichlorohydrin activated agarose matrix , Chinese  J. Chem. Eng. 1997, 5(1): 69-73.

74.  Xuejun Cao, Jiawen Zhu, Dawei Wang , Xingyan Wu  and Gance Dai, Purification of Urokinase by affinity Cross-flow Filtration Using a Water-Soluble Macroligand, Enzyme  Engineering  XIII,  New York  Annals of  Academic  and  Science, 1996,V799:454-459.

75.  WANG Jin-zhi,  CAO Xue-jun*, Purification of Kallikrein Using Reverse Micellar Extraction, China Biotechnology,  2007，27（1）:75-79 ( Chinese)

76.  Chen Lin-Jie,Cao Xue-Jun* Overcoming trypsin denaturation and precipitation during AOT/Isooctane reverse micellar extraction by adding ethanol，China Biotechnology,  2007，27（1）：75-79(Chinese)

77.  Jin Ke-Ming,Cao Xue-Jun*, Zhuang Ying-Ping,Chu Ju, Zhang Si-Liang*，Orawan  Duerasor，Phase transfer bioconversion of penicillin G into 6-APA by immobilized penicillin acylase in recycling aqueous two-phase systems with a light-sensitive copolymer,  J.  East China Univ. Sci. & Tech., 2007, 33(3): 318-322

78.  Jian-Hang Zhu, Dong-Zhi Wei, Xue-Jun Cao, and Zhong-Yi Yuan, Enzymatic synthesis of cephalexin integrated aqueous two-phase systems, Chinese J. Chem. Eng. 2003, 54(1):95-99 (Chinese)

79.  Yeqin Liu,  Diansheng  Xu, Xuejun Cao, Yuying Sang and Xiuping Zhang,  Purification of E.Coli. Recombinant Acidic Fibroblast Growth Factor，J. East China Univ. Sci. & Tech., 2001，27（4）:361-363(Chinese)

80.  Xuejun  Cao*, Yeqin Liu and XingYan Wu, Application of Membrane Technique in Pharmaceutical Industry(review).  World Notes on Antibiotics, 2000, 21(5): 212-214(Chinese)

81.  Haping He, Yeqin Liu and Xuejun Cao*, Penicillin Acylase Modified by PEG and its Application to Bioconversion in Aqueous Two-phase systems, J. East China Univ. Sci. & Tech., 2001, 27(1): 109-112 (Chinese).

82.   Hanping He and Xuejun Cao, Organic phase sensor, Chemical Sensor, 2000, 20(1):2-7(Chinese)

83.   Cao, X.J, Wu, X.Y., and Dai, G.C., Recovery of Urokinase from Human Urine by Precipitation with Zinc ion, J. East China Univ. Sci.& Tech.., 1998, 24（4）：427-430(Chinese).

84.   Cao, X.J, Tang, M., Wu, X.Y., and Dai,G.C., Purification of Urokinase by Affinity     Chromatography,  J. East China Univ. Sci. & Tech., 1998,24(5): 515-520(Chinese).

85.   Cao, X.J., Wu, X.Y., Zhu K.Y. and Dai, G.C., Affinity Chromatography of Urokinase Using Cefazolin as a ligand, J. Chinese Biochem. & Biophy., 1998,30(6): 635-637(Chinese, SCIE, 1999, Chinese).

86.   Jia Wen Zhu, Xue Jun Cao, Da Wei Wang, Xingyan Wu and Gan Ce Dai, Preparation of Water Soluble Macroligand and its Application, J. East China Univ. Sci. & Tech., 1999,25(6):563-566 (Chinese).

87.   Xuejun Cao, Xingyan Wu, Recovery of 6-aminopenicillanic Acid from Crystallization Mother Liquor Using Reverse Osmosis, J. Chinese Bioeng., 1998，14(4): 468-471(Chinese).

88.   Pang Zhengyu, Wu Xingyan, Cao Xuejun, Zhu Jiawen and Dai Gance, Affinity Chromatography Purification of Urokinase with a Polystyrene-based Medium, J. East China Univ. Sci. & Tech., 1996, 22(4): 417-421(Chinese).

89.   Zhou Xin, Cao Xuejun, Pang Zhengyu, Tang Meng, Wu Xingyan, Dai Gance, Isolation of Urokinase from Human Urine, Chinese J. Pharmaceuticals, 1996,27(8): 243-245(Chinese).

90.   Cao Xuejun, the Present & Future of the Chinese Scientific & Technological Strength, J.  East China Univ. Sci. & Tech., 1994, 4: 22-28 (Chinese).

91.  Cao Xuejun, Wu Xingyan, Jiang Yongling and Shen Qing, Penicillin Bioconversion in

    Aqueous Tow-phase Systems by Recombinant Escherichia Coli with Intracellular  Penicillin Acylase, Chinese J. Antibiotics, 1994, 19(2): 131-133.(Chinese).

92.  Cao Xuejun, Meng Xiangan, Liu Yanming, and Wu Xingyan, Study on Kenitic

    Behavior of E. Coli ATCC 11105 Producing Penicillin Acylase in Aqueous Two-phase  system, Chinese Antibiotics, 1994, 19(1): 3-5(Chinese).

93.  Cao Xuejun, Wu Xingyan, Studies on the Assay Method of Dextran Concentration in      

Aqueous Tow-phase Systems Proceeding Bioconversion with Penicillin Acylase, J. Chinese Antibiotics, 1994, 19(1): 61-62(Chinese).

94.  Cao Xuejun, He Chenliang, Two Main Test Items Analysis of Native Capreomycin

Product, Tianjin Pharmacy, 1989, 4: 14-15 (Chinese).

95.  Cao Xuejun, Chromatography,  in Biotechnology,  P157-181，Chemical Engineering

Publisher，Beijing, 2003.

96.  Cao Xuejun, Liu Yanming, and Wu Xingyan, Determination of Polyethylene Glycol in      

Aqueous Two-phase Systems, Chinese J. Analytical Chemistry, 1993, 21(12): 1470(Chinese).

97.  Cao Xuejun, He Chengliang, Zhang Baoping, A New Technique for Handling Pyrogen 

in Capreomycin Production, Chinese Pharmaceutical J., 1992(5): 288-289(Chinese).

CAO  Xue-Jun
Prof. & Ph.D, Vice Dean, School of Biotechnology，
State Key Laboratory of Bioreactor Engineering, Dept. Biochem.Eng.,
East China Univ. Sci. & Tech.,
130 Meilong Rd.,Shanghai, P.R.China 200237
Email :caoxj@ecust.edu.cn   
      caoxj2@sina.com