Zhong Li

  Room 1420, Research Building 18

  130 Meilong Road, Shanghai, 200237, China

  Phone: 021-64253984

  Email: lizhong@ecust.edu.cn

Professor and Ph.D. supervisor of ECUST. He is the dean of Shanghai Key Laboratory of Chemical Biology. His research interest focus on the development of pesticides, He is the main inventor of Paichongding and Cycloxaprid. He was awarded first and second prizes in Novel Product Innovation by China Crop Protection Industry Association. He got National High-level Personnel of Special Support Program, Youth Science and Technology Innovation Leader Leader, New Century Excellent Talents, Shanghai Leading Talents, Shanghai Outstanding Academic Leaders et al. He is in charge of dozens of research programs such as 863 program, sub-project of 973 and Natural Science Foundation of China. He published more than 100 papers as first or correspondence author in J. Agric. Food Chem., Insect Biochem. Mol. Biol., Environ. Sci. Technol. He filed about eighty patents including 14 PCT patents and 38 international patents. Twenty domestic patents and fifteen international patents were authorized. 

Recent Publications

1.    Yin Xu, Fukai Wang, Jilin Li, Xusheng Shao, Xiaoyong, Xu, Zhong Li*. Synthesis of novel imidazopyrrolo-fused isoxazole derivatives through acid-mediated intramolecular 1,3-dipolar cycloaddition. Synlett 2016, 27, 1397-1402

2.    Hui Zeng, Pengtao Yuan, Fukai Wang, Xiaoyong Xu, Xusheng Shao, Zhong Li*. A novel and selective synthetic approach for the access of pyrrolo[1,2-a] imidazol-7-one or pyrrol-3-one. Tetrahedron Lett. 2016, 57, 4031–4035

3.     Haibo Bao, Xusheng Shao, Yixi Zhang, Yayun Deng, Xiaoyong Xu, Zewen Liu, Zhong Li*. Specific Synergist for Neonicotinoid Insecticides: IPPA08, a cis-Neonicotinoid Compound with a Unique Oxabridged Substructure. J. Agric. Food Chem. 2016, 64, 5148–5155.

4.     Li Han, Yian Feng, Ming Luo, Zihao Yuan, Xusheng Shao, Xiaoyong Xu, Zhong Li*, 2,2,2-Trifluoroethanol activated one-pot Mannich-like reaction of b-nitroenamines, secondary amines, and aromatic aldehydes. Tetrahedron Lett. 2016, 57, 2727–2731.

5.     Ye Liu, Chao Lei, Xiaoyong Xu, Xusheng Shao, Zhong Li*. Design, synthesis and insecticidal activity of biphenyl-diamide derivatives, Chin. Chem. Lett. 2016, 27, 321-324.

6.     Jiling Li, Dang Wu, Xiaoyong Xu, Jin Huang, Xusheng Shao and Zhong Li*. Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1, 3-benzoazole derivatives bearing amide units. Bioorg. Med. Chem. Lett. 2016, 26, 3064-3066.

7.     Yefeng Fan, Wenwen Zhang, Xusheng Shao, Zhiping Xu, Xiaoyong Xu, Zhong Li*. Facile three-component synthesis and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine derivatives. Chin. Chem. Lett. 2015, 26 : 1-5.

8.     Yefeng Fan, Song Liu, Nanyang Chen, Xusheng Shao, Xiaoyong Xu, Zhong Li*. Oxidation Strategy for the Synthesis of Regioisomeric Spiroisobenzofuranopyrroles: Facile Entries to Spiro[isobenzofuran-1,2′-pyrrole] and Spiro[isobenzofuran-1,3′-pyrrole] Derivatives. Synlett. 2015, 26, 393-403.

9.     Yanpeng Lou, Gang Zhao*, Zhong Li*. Enantioselective direct mannich reactions of cyclic β-ketoesters catalyzed by chiral phosphine via a novel dual-reagent catalysis. Org. Lett. 2015, 17, 688-691.

10.   Baoyan Zhang, Zhiping Xu*, Yixi Zhang, Xusheng Shao, Xiaoyong Xu, Jiagao Cheng, Zhong Li*. Fipronil induces apoptosis through caspase-dependent mitochondrial pathways in Drosophila S2 cells. Pestic. Biochem. Physiol. 2015, 119, 81-89.

11.   Xuanqi Liu, Xiaoyong Xu, Chao Li, Hanxue Zhang, Qiuguo Fu, Xusheng Shao, Qingfu Ye*, Zhong Li*. Degradation of chiral neonicotinoid insecticide cycloxaprid in flooded and anoxic soil. Chemosphere, 2015, 119, 334-341.

12.   Xuanqi Liu, Xiaoyong Xu, Qingfu Ye*, Zhong Li*. Bioavailability and release of nonextractable (bound) residues of chiral cycloxaprid using geophagous earthworm metaphire guillelmi in rice paddy soil. Sci. Total Environ. 2015, 526: 243-250.

13.   Xuanqi Liu, Xiaoyong Xu, Chao Li, Hanxue Zhang, Qiuguo Fu, Xusheng Shao, Qingfu Ye*, Zhong Li*. Assessment of the Enviromental Fate of Cycloxaprid in Flooded and Anaerobic Soils by Radioisotopic Tracing. Sci. Total Environ.. 2016, 543: 116-122.

14.   Renbo Xu, Rui Xia, Ming Luo, Xiaoyong Xu*, Jiagao Cheng, Xusheng Shao, Zhong Li*. Design, Synthesis, Crystal Structures, and Insecticidal Activities of Eight-Membered Azabridge Neonicotinoid Analogues. J. Agric. Food Chem., 2014, 62(2), 381–390