Yuhong Ren

Ren Yuhong,

Ph.D., Professor, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.

EDUCATION
2009-2010: Visiting Scholar in Biomedical Engineering Department, Northwestern University, USA.

2001-2004 Ph.D. in Biochemical Engineering, East China University of Science and Technology （ECUST）

1988-1991 M.S. in Inorganic Chemistry, ECUST

1984-1988 B.S. in Chemistry, University of Electronic Science and Technology of China (EUSTC)

RESEARCH FIELDS AND EXPERIENCE
2001-present  Professor of State Key Laboratory of Bioreactor Engineering, ECUST
1) Biomaterial: Bio-adhesive materials which inspired from adhesive proteins secreted by marine mussels.

2) Self-assembly of multi-enzymes system and Biosynthesis: Self-assembly of multi-enzymes system in vitro and in vivo. Synthesizing chiral medical intermediates using cells or enzymes
3) Natural Products: Screening new natural products in dermocosmetic such as for anti-acne activity, anti-histamine activity, etc.

1991-2000: Instructor and Associate Professor of the Jiangxi-OAI Institute,
1) Synthesized several fine-chemical compounds such as spices, antiseptic, etc.
2) Studied of organic chemistry synthesis.

SELECTED PUBLISHED PAPERS (* corresponding author)

1．Xin Gao, Chengcheng Zhao, Ting Yu, Shengli Yang, Yuhong Ren*, Dongzhi Wei*. Construction of a Reusable Multi-enzyme Supramolecular Device via Disulfide Bond Locking. Chemical Communications. 2015, 51, 10131-10133.

2．Jianbing Yang, Kefeng Ni, Yuhong Ren*. One-Step Purification and Immobilization of His-tagged Protein via Ni2+-functionalized Fe3O4@Polydopamine Magnetic Nanoparticles. Biotechnology and Bioprocess Engineering.    

3．Zhongwei Guo, Kefeng Ni, Dongzhi Wei, Yuhong Ren*. Fe3+-induced oxidation and coordination cross-linking in catechol-chitosan hydrogels under acidic pH conditions. RSC Advances, 2015, 5, 37377-37384.

4．Ting Yu, Xin Gao,Yuhong Ren*, Dongzhi Wei. Assembly of cellulases with synthetic proteinscaffolds in vitro. Bioresources and Bioprocessing. 2015, 2:16. DOI 10.1186/ s40643- 015- 0046-8.

5．Dongshuang Wang, Kefeng Ni, Yuhong Ren*, Dongzhi Wei. Site-directed Modification of Geneti -cally Engineered Proteus sp. Lipase K107 Variants with a Polyethylene Glycol Derivative. Journal of Molecular Catalysis B: Enzymatic. 2015,111, 36-42.

6．Xin Gao, Shuai Yang, Chengcheng Zhao, Yuhong Ren*, Dongzhi Wei*. Artificial Multienzyme Supramolecular Device: Highly Ordered Self-assembly of Oligomeric Enzymes In Vitro and In Vivo. Angewandte Chemie. 2014, 53, 14027-14030.

7．Xin Gao, Kefeng Ni, Chengcheng Zhao, Yuhong Ren*, Dongzhi Wei*. Enhancement of immobilized enzyme activity on polydopamine-coated iron oxide nanoparticles by rational orientation of formate dehydrogenase. Journal of Biotechnology. 2014, 188, 36-41.

8．Wenwen Cai, Erzheng Su, Shujing Zhu, Yuhong Ren*, Dongzhi Wei. Characterization of a nitrilase from Arthrobacter aurescens CYC705 for synthesis of imino-diacetic acid. Journal of General Applied Microbiology. 2014, 60, 207-214.

9．Jiufeng Lin , Kefeng Ni , Yang Zhang , Dongzhi Wei, Yuhong Ren*. Synthesis and Evaluation of Transdermal Permeation, PharmACOlogical Activity of Bornyl NSAID Esters. Letters in Drug Design & Discovery. 2014, 11, 72-77.

10.  Kefeng Ni1, Jianbing Yang1, Yuhong Ren1,*, Dongzhi Wei1,* Facile Synthesis of Glutathione Functionalized Fe3O4@Plydopamine for Separation of GST-tagged Protein. Materials Letters. 2014, 128, 392-395.

11.  Kefeng Ni, Hualei Wang, Li Zhao, Minjie Zhang, Siyuan Zhang, Yuhong Ren*, Dongzhi Wei. Efficient production of (R)-(-)-mandelic acid in biphasic system by immobilized recombinant E. coli, Journal of Biotechnology. 2013,137(4): 433-440

12．Xu Zhou, Kefeng Ni, DongZhi Wei and Yuhong Ren*. Nano-ZnO induced flocculation of Saccharomyces cerevisiae, Advanced Materials Research. 2013,749:172-176.

13．Cunxun Wang, Kefeng Ni, Xu Zhou, Dongzhi Wei，Yuhong Ren*. Immobilization of Gluconobacter oxydans by Entrapment in Porous Chitosan Sponge, Bioprocessing and Biotechniques. 2013,3:2

14. Kefeng Ni,a, 1Huimin Lu,^{a, 1} Cunxun Wang,^a Kvar C.L. Black,^{b, c} Dongzhi Wei,^a Yuhong Ren,^a, * Phillip B. Messersmith^{b, c, 2}. A novel technique for in situ aggregation of Gluconobacter oxydans using bio-adhesive magnetic nanoparticles. Biotechnology and Bioengineering.  2012, 109(12): 2970-2977.

15. Kefeng Ni; Xu Zhou; Li Zhao; Hualei Wang; Yuhong Ren^*; Dongzhi Wei. Magnetic catechol-chitosan with bioinspired adhesive surface: Preparation and immobilization of ω-transaminase. PLoS one. 2012, 7(7): e41101.

16. Yuhong Ren*, Jose G. Rivera, Lihong He, Harsha Kulkarni, Dong-Keun Lee?, Phillip B. Messersmith*. Facile, high efficiency immobilization of lipase enzyme on magnetic iron oxide nanoparticles via a biomimetic coating. BMC Biotechnology.2011, 11:63

17．Shiyu Fu, Changlei Sun, Xingyi Tao and Yuhong Ren*. Anti-inflammatory effects of active constituents extracted from Traditional Chinese Medicine herbs against Propionibacterium acnes. Natural Product Research. 2012, 26(18): 1746-9.

18.  Jiaqi Wang , Xinyi Tao , Yufei Zhang, Dongzhi Wei, Yuhong Ren*. Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl- chitosan nanoparticles. Biomaterials. 2010, 31，4426–4433.

19.   Yuhong Ren, Yong Wang, Yufei Zhang, Dongzhi Wei ^*.Overcoming multidrug resistance in a human carcinoma cells by an antisense oligodeoxynucleotide-doxorubicin conjugate in vitro and in vivo. Molecular Pharmaceutics.2008，5（4）：579-587.

20. Jianguo Zhang, XuedongWang, Erzheng Su, Guochen Fang, Yuhong Ren, DongzhiWei. A new fermentation strategy for S-adenosylmethionine production in recombinant Pichia pastoris. Biochemical Engineering Journal 41 (2008) 74–78

E-mail address: yhren@ecust.edu.cn