Xusheng Shao

  Room 1410, Research Building 18

  130 Meilong Road, Shanghai, 200237, China

  Phone: 021-64253967

  Email: shaoxusheng@ecust.edu.cn

Associated professor and Ph.D. supervisor of ECUST. He got his Ph. D. degree in Applied Chemistry at ECUST in 2009. From 2012 to 2013, he entered John E. Casida’s lab at UC-Berkeley to study pesticide toxicology and metabolism. Centering on crop protection, the applicator engages in the basic research on green pesticides and their applications in crop protection, biological mechanism of insecticides, the modulation of insecticidal target proteins and the development and applications of novel insecticides. He published more than seventy papers including thirty-six papers as first or correspondence author in PNAS, J. Agric. Food Chem., Insect Biochem. Mol. Biol. and J. Org. Chem. He filed about thirty-nine patents including five domestic authorized patents and ten international authorized patents. He is one of the inventors of commercialized insecticides Paichongding and Cycloxaprid. He is in charge of several research programs such as Natural Science Foundation of China and Australia DC Foundation. He was awarded first and second prizes in Novel Product Innovation by China Crop Protection Industry Association. He is supported by the Youth Talent of university and Shanghai Pujiang Program. He now is the youth editorial member of Chinese Chemical Letters and the member of American Chemical Society. 

Recent Publications

        1. Xue Tian, Chao Zhang, Qi Xu, Zhong Li and Xusheng Shao*. Azobenzene-Benzoylphenylureas as Photoswitchable Chitin Synthesis Inhibitors. Org. Biomol. Chem. 2017, DOI: 10.1039/C6OB02813F.

        2. Runjiang Song, Yian Feng, Donghui Wang, Zhiping Xu, Zhong Li, Xusheng Shao*.Phytoalexin Phenalenone Derivatives Inactivate Mosquito Larvae and Root-knot Nematode as Type-Ⅱ Photosensitizer. Sci. Rep. 2017, 7, 42058.

        3. Ye Liu, Xinfei Chen, Xiaoyong Xu, Jiagao Cheng, Xusheng Shao*, and Zhong Li* Design, Synthesis and Insecticidal Activity of Diamides with Oxydibenzene or Diphenylamine Subunits. Lett. Drug Des. Discov. 2017，DOI: 10.2174/1570180813666161028113852.

        4. Yian Feng, Minming Zou, Runjiang Song, Xusheng Shao*, Zhong Li, Xuhong Qian. Formation of 1,4,2-Dithiazolidines or 1,3-Thiazetidines from 1,1-Dichloro-2-nitroethene and Phenylthiourea Derivatives. J. Org. Chem. 2016, 81, 10321-10327.

        5. Shen Li, Runjiang Song, Donghui Wang, Xue Tian, Xusheng Shao*, Zhong Li. Azopyridine-imidacloprid derivatives as photoresponsive neonicotinoids. Chin. Chem. Lett. 2016, 27, 635-639.

        6. Feilong Sun, Xusheng Shao*, Zhong Li. Access of Indenofurans and Indenopyridines via Annulation of Heterocyclic Ketene Aminals, o-Phthalaldehyde and cyclic 1.3-diketones. RSC Advance 2016, 6, 15382-15389.

        7. Fengjuan Zhu, Runjiang Song, Shen Li, Xusheng Shao*. In-water Synthesis of Quinazolinones from 1,1-Dichloro-2-nitroethene and Anthranilamides. Synlett 2016, 27, 2167-2170.

        8. Ye Liu, Chao Lei, Xiaoyong Xu, Xusheng Shao*, Zhong Li*. Design, synthesis and insecticidal activity of biphenyl-diamide derivatives, Chin. Chem. Lett. 2016, 27, 321-324.

        9. Jiling Li, Dang Wu, Xiaoyong Xu, Jin Huang, Xusheng Shao* and Zhong Li*. Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1, 3-benzoazole derivatives bearing amide units. Bioorg. Med. Chem. Lett. 2016, 26, 3064-3066.

        0. Fengjuan Zhu, Xue Tian, Xusheng Shao*, Zhong Li. Direct Amidation of Aniline Derivatives with 1,1-Dichloro-2-nitroethene in Water. Tetrahedron Lett. 2015, 56, 5945-5949.

        11. Zhiping Xu, Lina Shi, Danping Jiang, Jiagao Cheng, Xusheng Shao*, Zhong Li. Azobenzene Modified Imidacloprid Derivatives as Photoswitchable Insecticides: Steering Molecular Activity in a Controllable Manner. Sci. Rep. 2015, 5, 13962.

        12. Fengjuan Zhu, Minming Zou, Xusheng Shao*, Zhong Li. On-water, Catalyst-Free and Room-temperature Construction of 2-Aryl-1,3,4-oxadiazole Derivatives from 1,1-Dichloro-2-nitroethene and Hydrazides. RSC Advance 2015, 5, 61752-61758.

        13. Feilong Sun, Fengjuan Zhu, Xusheng Shao*, Zhong Li. One-pot and Three-components Synthesis of 1,8-Naphthyridine Derivatives from Heterocyclic Ketene Aminals, Malononitrile Dimer and Aryl Aldehydes. Synlett 2015, 26, 2306-2312.

        14. Nanyang Chen, Xiaoqing Meng, Fengjuan Zhu, Jiagao Cheng, Xusheng Shao*, Zhong Li. Tetrahydroindeno[1’,2’:4,5]pyrrolo[1,2-a]imidazol-5(1H)-ones as Novel Neonicotinoid Insecticides: Reaction Selectivity and Substituent Effects on the Activity Level. J. Agric. Food Chem. 2015, 63, 1365-1369.

        15. Jiling Li, Zhicheng Zhang, Xiaoyong Xu, Xusheng Shao*, Zhong Li*. Nematicidal Activities of Diamides with Diphenylacetylene Scaffold against Meloidogyne Incognita. Aust. J. Chem. 2015, 68, 1543-1549.

        16. Jiling Li, Xiaoyong Xu, Xusheng Shao*, Zhong Li*. A Novel Colorimetric Fluoride Sensor Based on a Semi-rigid Chromophore Controlled by Hydrogen Bonding, Luminescence, 2015, 30, 1285-1289.

        17. Minming Zou, Xue Tian, Nanyang Chen, Xusheng Shao*. Nematicidal Activity of Sprio and Bridged Heterocyclic Neonicotinoid Analogues against Meloidogyne incognita. Lett. Drug Des. Discov. 2015, 12, 439-445.

        18. Yefeng Fan, Song Liu, Nanyang Chen, Xusheng Shao*, Xiaoyong Xu, Zhong Li*. Oxidation strategy for the synthesis of regioisomeric spiroisobenzofuranopyrroles: facile entries to spiro[isobenzofuran-1,2’-pyrrole] and spiro[isobenzofuran-1,3’-pyrrole] derivatives. Synlett 2015, 26, 393-403.

        19. Nanyang Chen, Shanshan Xia, Minming Zou, Xusheng Shao*. Bridged heterocyclic neonicotinoid analogues: design, synthesis, and insecticidal activity. Res. Chem. Intermed. 2015, 41, 5293-5300.