Ping Shi

Ping Shi, Ph.D. Professor in State Key Laboratory of Bioreactor Engineering, EastChinaUniversityof Science and Technology.

Education 

BSc, School of Life Sciences,ShanxiNormalUniversity,Xi'an,China, Jul. 1995

MSc,SchoolofLife Sciences,LanzhouUniversity,Lanzhou,China, Jul. 1998 (Developmental Biology and Biochemistry Major)

Ph.D, College of Chemistry and chemical Engineering, Lanzhou University, Lanzhou, China, Jul. 2001 (Biochemistry Major)

Research & Working Experience

Sep.2001- Jul.2003, Postdoctoral Fellow, School of Life Sciences, Xiamen University, Xiamen, China

Jul. 2003 - April 2006, Associate Professor, State Key Laboratory of Bioreactor Engineering,EastChinaUniversityof Science and Technology,Shanghai,China

Jan. 2005 - Jan. 2008, Visiting Investigator of Northwest Institute of Plateau Biology,ChineseAcademyof Sciences,Xining,China

April 2006 – Sep. 2009, Postdoctoral fellow, Department of Hematopathology, The University of Texas M. D. Anderson Cancer Center,Houston,Texas

Sep.2009-Present, Professor, State Key Laboratory of Bioreactor Engineering,EastChinaUniversityof Science and Technology,Shanghai,China

Professional Membership/Activities

Member, Chinese Society for Cell Biology, 2002-present

Member, American Association for Cancer Research, 2007-present

Member, Women in Cancer Research (WICR), American Association for Cancer Research, 2007-present

RESEARCH INTERESTS

Signaling pathway study on the bioreaction process

Studies on cellular target pathways of bioactive compounds

Biomarker assays for diagnostic and prognostic applications in cancer

Selected Publications

1. Chunchang Zhao*, Xiuli Zhang, Kaibin Li, Shaojia Zhu, Zhiqian Guo, Lili Zhang, Feiyi Wang, Qiang Fei, Sihang Luo, Ping Shi*, He Tian and Wei-Hong Zhu*, Förster Resonance Energy Transfer Switchable Self-Assembled Micellar Nanoprobe: Ratiometric Fluorescent Trapping of Endogenous H2S Generation via Fluvastatin-Stimulated Upregulation, J. Am. Chem. Soc. DOI: 10.1021/ jacs.5b03248
2. Yongping Gao , Yongsheng Li*, Jianzhuang Chen, Shaojia Zhu, Xiaohang Liu, Liangping Zhou, Ping Shi, Dechao Niu, Jinlou Gu, Jianlin Shi*, Multifunctional gold nanostar-based nanocomposite: Synthesis and application for noninvasive MR-SERS imaging-guided photothermal ablation, Biomaterials 2015, 60, 31-41
3. Zhijia Fang, Xin Kuang, Youshang Zhang, Ping Shi*, Zhiwei Huang*, AnovelHAC1-based dual-luciferase reporter vector for detecting endoplasmic reticulum stress and unfolded protein response in yeast Saccharomyces cerevisiae, Plasmid 2015, 79, 48–53
4.  Andong Shao, Yongshu Xie, Shaojia Zhu, Zhiqian Guo*, Shiqin Zhu, Jin Guo, Ping Shi, Tony D. James, He Tian, and Wei-Hong Zhu Far-Red and Near-Infrared AIE-Active Fluorescent Organic Nanoprobes with Enhanced Tumor-Targeting Efficacy: Shape-Specific Effects, Angew. Chem. Int. Ed. 2015, 54, 1 – 7
5. Zhiyuan Xu, Shaojia Zhu, Mingwei Wang, Yongjun Li, Ping Shi*, and Xiaoyu Huang*, Delivery of Paclitaxel Using PEGylated Graphene Oxide as a Nanocarrier. ACS Applied Materials & Interfaces, 2015, 7, 1355–1363
6. Zhanzhan Liu, Shaojia Zhu, Yongjun Li, Yongsheng Li*, Ping Shi*, Zhong Huang and Xiaoyu Huang*, Preparation of graphene/poly(2-hydroxyethyl acrylate) nanohybrid materials via an ambient temperature “grafting-from” strategy. Polym. Chem. 2015, 6, 311-321
7. Beibei Li, Hong Zhen, Xiaoyan Zhang, Song Wang, Yifei Zhang, Zhijia Fang, Zhiwei Huang*, Ping Shi*, Probiotic properties of Enterococcus strains isolated from the silage, J. Food Saf. 2015, 35, 108–118
8. Shaojia Zhu, Hong Zhen, Yongjun Li, Ping Wang, Xiaoyu Huang, Ping Shi*, PEGylated graphene oxide as a nanocarrier for podophyllotoxin. J. Nanopart. Res. 2014, 16, 2530
9. Hong Zhen, Yifei Zhang, Zhijia Fang, Zhiwei Huang*, Chongge You, Ping Shi*,Toona sinensis and Moschus decoction induced cell cycle arrest in human cervical carcinoma HeLa cells, Evid.-based Complement Altern. Med. 2014,  http://dx.doi.org/10.1155/2014/121276
10. Song Wang, Xin Kuang, Zhijia Fang, Zhiwei Huang*, Ping Shi*, Effect of oleic acid on the levels of eight metal ions in human hepatoma SMMC-7721 Cells, Biol. Trace Elem. Res.2014, 159, 445–450
11. Andong Shao, Zhiqian Guo,* Shaoji Zhu, Shiqin Zhu, Ping Shi, He Tian and Weihong Zhu* Insight into aggregation-induced emission characteristics of red-emissive quinoline-malononitrile by cell tracking and real-time trypsin detection. Chem. Sci., 2014, 5, 1383-1389.
12. Zhiyuan Xu, Song Wang, Yongjun Li*, Mingwei Wang, Ping Shi*, Xiaoyu Huang*, Covalent Functionalization of Graphene Oxide with Biocompatible Poly (ethylene glycol) for Delivery of Paclitaxel, ACS Appl. Mater. Interfaces 2014, 6, 17268?17276
13. Zhijia Fang, Min Zhao, Hong Zhen, Lifeng Chen, Ping Shi*, Zhiwei Huang*, Genotoxicity of tri- and hexavalent Chromium Compounds in vivo and their modes of action on DNA damage in vitro, PLoS ONE 2014, 9, e103194
14. Zhiwei Huang*, Zhijia Fang, Hong Zhen, Li Zhou, Hesham M. Amin, Ping Shi*, Inhibition of type I insulin-like growth factor receptor tyrosine kinase by picropodophyllin induces apoptosis and cell cycle arrest in T lymphoblastic leukemia/lymphoma, Leuk. Lymphoma 2014, 55, 1876–1883
15. Zhiwei Huang*, Xin Kuang, Zhongxiang Chen, Zhijia Fang, Song Wang, Ping Shi*, Comparative studies of tri- and hexavalent chromium cytotoxicity and their effects on oxidative state of Saccharomyces cerevisiae cells, Curr. Microbiol. 2014, 68, 448–456
16. Zhijia Fang, Song Wang, Xiuxiu Du, Ping Shi*, Zhiwei Huang*, Phosphatidate phosphatase-1 is functionally conserved in lipid synthesis and storage from human to yeast, Acta Biol. Hung. 2014, 65, 481–492 
17. Si Yao, Andong Shao, Wenru Zhao,* Shaojia Zhu, Ping Shi, Zhiqian Guo,* Weihong Zhu and Jianlin Shi*，Fabrication of mesoporous silica nanoparticles hybridised withfluorescent AIE-active quinolinemalononitrile for drug delivery and bioimaging，RSC Adv. 2014, 4, 58976–58981
18. Suraj Konnath George, Deeksha Vishwamitra，Roxsan Manshouri，Ping Shi and Hesham M. Amin*, The ALK inhibitor ASP3026 eradicates NPM-ALK+ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model, Oncotarget 2014, 5, 5750-5763
19. Bin Shi, Deeksha Vishwamitra, J. Gabrielle Granda, Thomas Whitton, Ping Shi, and Hesham M. Amin. Molecular and functional characterizations of the association and interactions between nucleophosmin-anaplastic lymphoma kinase and type I insulin-like growth factor receptor. Neoplasia. 2013, 15, 669-683
20. Zhiyuan Xu, Yongjun Li, Ping Shi*, Bochan Wang, Xiaoyu huang. Functionalized graphene oxide as a nanocarrier for loading and delivering of eriocalyxin B. Chinese J Organic Chem. 2013, 33, 2162-2168
21. Zhiyuan Xu, Yongjun Li, Ping Shi*, Bochan Wang, Xiaoyu Huang. Functionalized graphene oxide as a nanocarrier for loading and delivering of oridonin. Chinese J Organic Chem. 2013, 33, 573-580
22. Bochan Wang, Lifeng Chen, Hong Zhen, Li Zhou, Ping Shi*, Zhiwei Huang. Proteomic Changes Induced by Podophyllotoxin in Human Cervical Carcinoma HeLa Cells. Am J Chinese Med 2013, 41: 163–175

CONTACT INFORMATION

PING SHI

Experimental Building #18, Room 1315

State Key Laboratory of Bioreactor Engineering

East ChinaUniversity of Science and Technology

130 Meilong Road,Shanghai 200237,China

86-21-64251655 (phone); 86-21-64252920 (fax)

caplab@ecust.edu.cn