Dongzhi Wei

Education

1980-1984  B.Eng., Biochemical Engineering, East China University of Science & Technology

1984-1989  Ph.D., Biotechnology, East China University of Science & Technology

Academic Careers

1989-1995   Lecture/Associate Professor of Biotechnology, East China University of Science & Technology

1995-       Professor of Biotechnology, East China University of Science & Technology

1992-1995   Deputy Director, Institute of Biochemical Engineering, East China University of Science & Technology

1995-2001   Director, Institute of Biochemistry, East China University of Science & Technology

2001-2007   Dean, College of Biotechnology, East China University of Science & Technology

2001-       Director, Newworld Institute of Biotechnology, East China University of Science & Technology

Publications

1.Xin Gao, Shuai Yang, Chengcheng Zhao, Yuhong Ren*, Dong-Zhi Wei*，Artificial multienzyme supramolecular device: highlyordered self-assembly of oligomeric enzymes in vitro and in vivo，Angewandte Chemie，2014，126（51）：14251-14254.

2.Yao, Kang，Xu, Li-Qin，Wang, Feng-Qing*，Wei, Dong-Zhi*，Characterization and engineering of 3-ketosteroid-Delta(1)-dehydrogenase and 3-ketosteroid-9 alpha-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9 alpha-hydroxy-4-androstene-3,17-dione through the catabolism of sterols，Metabolic Engineering，2014，24：181-191.

3.Zhang, Lujia，Tang, Xiaomang，Cui, Dongbing，Yao, Zhiqiang，Gao, Bei，Jiang, Shuiqin，Yin, Bo，Yuan, Y. Adam，Wei, Dongzhi*， A method to rationally increase protein stability based on the charge-charge interaction, with application to lipase LipK107，Protein Science，2014，23（1）：110-116.

4.Yin, Bo，Cui, Dongbing，Zhang, Lujia，Jiang, Shuiqin，Machida, Satoru，Yuan, Y. Adam*，Wei, Dongzhi*，Structural insights into substrate and coenzyme preference by SDR family protein Gox2253 from Gluconobater oxydans，Proteins: Structure, Function, and Genetics，2014，82（11）：2925-2935.

5.Liu, Xu，Wang, Chao，Zhang, Lujia，Yao, Zhiqiang，Cui, Dongbing，Wu, Liang，Lin, Jinping*，Yuan, Yu-Ren Adam，Wei, Dongzhi*，Structural and mutational studies on an aldo-keto reductase AKR5C3 from Gluconobacter oxydans，Protein Science，2014，23（11）：1540-1549.

6.Gao, Xin，Ni, Kefeng，Zhao, Chengcheng，Ren, Yuhong*，Wei, Dongzhi*，Enhancement of the activity of enzyme immobilized on polydopamine-coated iron oxide nanoparticles by rational orientation of formate dehydrogenase，Journal of Biotechnology，2014，188：36-41.

7.You PY, Qiu J, Su EZ, Wei DZ*, Carica papaya Lipase Catalysed Resolution of β-Amino Esters for the Highly Enantioselective Synthesis of (S)-Dapoxetine, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 3: 557-565.

8.Ni K, Zhou X, Zhao L, Wang HL, Ren YH*, Wei DZ*, Magnetic Catechol-Chitosan with Bioinspired Adhesive Surface: Preparation and Immobilization of v-Transaminase, PLoS ONE, 2012, 7(7) :e41101.

9. Zhang C, Fan K, Zhang W, Zhu R, Zhang L, Wei DZ*. Structure-based characterization of canine-human chimeric uricases and its evolutionary implications. BIOCHIMIE. 2012,94 (6):1412-1420.

10.Yao K, Wang FQ, Zhang HC, Wei DZ*. Identi?cation and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum. METABOLIC ENGINEERING, 2013,15:75–87.

11.Liu X, Yuan Z, Yuan Y, Lin JP, Wei DZ*. Biochemical and structural analysis of Gox2181, a new member of the SDR superfamily from Gluconobacter oxydans. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011,415(2): 410-415.

12.Wang JQ, Tao XY, Zhang YF, Wei DZ* ,Ren YH* et al. Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl-chitosan nanoparticles. BIOMATERIALS 31(15):4426-4433     MAY 2010  (IF7.365)

13.Zhang J, Shen YL, Liu JW, Wei DZ* et al, Antimetastatic effect of prodigiosin through inhibition of tumor invasion, BIOCHEMICAL PHARMACOLOGY 69(3):407-414 FEB 1 2005 (IF 4.838)

14.Ren YH, Wang Y, Zhang YF, Wei DZ* et al, Overcoming multidrug resistance in human carcinoma cells by an antisense oligodeoxynucleotide-doxorubicin conjugate in vitro and in vivo, Conference Information: 7th International Symposium on Polymer Therapeutics, MAY 26-28, 2007 Ctr Invest Principe Felipe, Valencia, SPAIN, MOLECULAR PHARMACEUTICS  5(4) :579-587  JUL-AUG  2008  (IF 4.565)

15.Wang FQ, Zhang CG, Li B, Wei DZ, Tong WY*, New Microbiological Transformations of Steroids by Streptomyces virginiae IBL-14, ENVIRONMENTAL SCIENCE & TECHNOLOGY 43(15):5967-5974 AUG 2009  (IF 4.458)