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2017


1. Jiao XC, Pan J, Kong XD, Xu JH*. Protein engineering of aldolase LbDERA for enhanced activity toward real substrates with a high-throughput screening method coupled with an aldehyde dehydrogenase. Biochem. Biophys. Res.Commun., 2017, 482(1):159-163. 

                         


2. Zheng MM, Chen KC, Wang RF, Li H, Li CX*, Xu JH*. Engineering 7β-Hydroxysteroid Dehydrogenase for Enhanced Ursodeoxycholic Acid Production by Multiobjective Directed Evolution. J. Agric. Food Chem.2017, 15;65(6):1178-1185.


3. Zheng YC, Xu JH, Wang H, Lin GQ, Hong R*, Yu HL*.Hydroxynitrile Lyase Isozymes from Prunus communis: Identification, Characterization and Synthetic Applications. Adv. Synth. Catal. 2017, 359 (7) :1185-1193.


4. Shang YP, Chen Q, Kong XD, Zhang YJ, Xu JH,  Yu HL*. Efficient Synthesis of (R)‐2‐Chloro‐1‐(2,4‐dichlorophenyl)ethanol with a Ketoreductase from Scheffersomyces stipitis CBS 6045.Adv. Synth. Catal. 2017, 359(3): 426–431.


5. Li M#, Zhang ZJ#, Kong XD, Yu HL, Zhou JH, Xu JH*. EngineeringStreptomyces coelicolor carbonyl reductase for efficient synthesis of atorvastatin precursor. Appl. Environ. Microbiol., 2017, 83 (12) :e00603-17.


6. Chen KC, Zheng MM, Pan J, Li CX, Xu JH*. Protein engineering and homologous expression of Serratia marcescens lipase for efficient biosynthesis of a pharmaceutically relevant chiral epoxyester. Appl. Biochem. Biotechnol.,  DOI: 10.1007/s12010-017-2543-z. Accepted.

 

7. Zhang C, Pan J, Li CX, Bai YP*, Xu JH *. Asymmetric bioreduction of keto groups of 4- and 5-Oxodecanoic acids/esters with a new carbonyl reductase. Catalysis Communications. 2017, 102, 35-39.

 

8. Bai YP, Cheng H, Xu JH*. Recent advances in discovery, engineering and applications of organophosphorus hydrolases. Acta Microbiologica Sinica. 2017, 57(8): 1168-1179.

 

9. Zheng GW, #, * Liu YY#, Chen Q#, Huang L, Yu HL, Lou WY, Li CX, Bai YP, Li AT and Xu JH*. Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1. ACS Catal., 2017, 7: 7174-7181.

 

10. Gong XM, Zheng GW*, Liu YY and Xu JH*Identification of a robust carbonyl reductase for diastereoselectively building syn-3,5-dihydroxy hexanoate: a bulky side chain of atorvastatin. Org. Process Res. Dev. 2017, DOI: 10.1021/acs.oprd.7b00194

 

11. Li HTian P, Xu JH*, Zheng GW*. Identification of an imine reductase for asymmetric reduction of bulky dihydroisoquinolines. Org. Lett., 2017, 19(12): 3151−3154.

 

12. Jiang Y, Shang YP, Li H, Zhang C, Pan J, Bai YP, Li CX* and Xu JH*. Enhancing transglutaminase production of Streptomyces mobaraensis by iterative mutagenesis breeding with atmospheric and room-temperature plasma (ARTP). Bioresour. Bioprocess. 2017, 4: 37.


13.  Bai YP*, Luo XJ, Zhao YL, Li CX, Xu DS, Xu JH*(2017). Efficient degradation of malathion in the presence of detergents using an engineered organophosphorus hydrolase highly expressed by Pichia pastoris without methanol induction. J. Agric. Food Chem., 2017, 65(41):9094-9100.


14. Zheng M-M, Chen F-F, Li H, Li C-X,* Xu J-H*(2017). Continuous production of ursodeoxycholic acid by using two cascade reactors with co-immobilized enzymes. ChemBioChem. 18, 1-8.  


15. Yu HL, Li T, Chen FF, Luo XJ, Li AT, Zheng GW, Xu JH* (2017). Ammonium donating amination of alkane by a sustainable multi-enzyme cascade “artificial metabolism”. Metabolic Engineering, 47: 184-189.





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