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2015

1. Chen FF, Liu YY, GW Zheng*, Xu JH*. Asymmetric amination of sec-alcohols using a redox-neutral two-enzyme cascade. ChemCatChem, 2015, 7: 3838-3841. (Highlighted by Nature Chemistry 2015, 7, 948)

 http://onlinelibrary.wiley.com/doi/10.1002/cctc.201500785/full 

2. Sun Z, Lonsdale R, Kong XD, Xu JH, Zhou J*, Reetz MT* (2015). Reshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: Use of smallest amino acid alphabets in directed evolution. Angew. Chem. Int. Ed., 54:12410-12415.

http://onlinelibrary.wiley.com/doi/10.1002/anie.201501809/abstract

3. Li H, Luan ZJ, Zheng GW*, Xu JH* (2015). Efficient synthesis of chiral indolines using an imine reductase from Paenibacillus lactis. Advanced Synthesis & Catalysis, 357: 1692-1696.

http://onlinelibrary.wiley.com/doi/10.1002/adsc.201500160/abstract

 

4. Zhang YJ, Zhang WX, Zheng GW*, Xu JH* (2015). Identification of an ε-keto ester reductase for the efficient synthesis of an (R)-α-Lipoic acid precursor. Advanced Synthesis & Catalysis, 357: 1697-1702.

http://onlinelibrary.wiley.com/doi/10.1002/adsc.201500001/abstract

 

5. Luan ZJ, Li FL, Dou S, Chen Q, Kong XD, Zhou JH, Yu HL*, Xu JH* (2015). Substrate channel evolution of esterase for the synthesis of cilastatin. Catal. Sci. Technol., 5: 2622-2629.

http://pubs.rsc.org/en/Content/ArticleLanding/2015/CY/C5CY00085H

 

6. Jiao XC, Pan J*, Xu GC, Kong XD, Chen Q, Zhang ZJ, Xu JH* (2015). Efficient synthesis of a statin precursor in high space-time yield by a new aldehyde-tolerant aldolase identified from Lactobacillus brevis. Catal. Sci. Technol., 5: 4048-4054.

http://pubs.rsc.org/en/content/articlelanding/2015/cy/c5cy00537j#!divAbstract

7. Luan ZJ, Yin YC, Li AT, Yu HL*, Xu JH* (2015). Monoterpene hydroxylation with an artificial self-sufficient P450 utilizing a P450SMO reductase domain for the electron transfer. J Mol Catal B: Enzym, 116: 78-82.

http://www.sciencedirect.com/science/article/pii/S1381117715000478

 

8. Wu YW, Kong XD, Zhu QQ, Fan LQ*, Xu JH* (2015). Chemoenzymatic enantioconvergent hydrolysis of p-nitrostyrene oxide into (R)-p-nitrophenyl glycol by a newly cloned epoxide hydrolase VrEH2 from Vigna radiate. Catal. Commun., 58: 16−20.

 http://www.sciencedirect.com/science/article/pii/S1566736714003240 

9. Chen Q, Luan ZJ, Cheng X*, Xu JH* (2015). Molecular dynamics investigation of the substrate binding mechanism in caroxylesterase. Biochemistry, 54: 1841-1848.

http://pubs.acs.org/doi/abs/10.1021/bi5015612

10. Chen Q, Luan ZJ, Yu HL, Cheng X*, Xu JH* (2015). Computation-based analysis of catalytic efficiency and rational design of a carboxylic esterase RhEst1. Journal of Molecular Graphics and Modelling, 62: 319–324.

http://www.sciencedirect.com/science/article/pii/S1093326315300759 

11.  Fan CW, Ma BD, Xu GC, Bai YP, Zhang J, Xu JH* (2015). A novel D-mandelate dehydrogenase used in three-enzyme cascade reaction for highly efficient synthesis of non-natural chiral amino acids. Journal of Biotechnology, 195: 67-71. 

http://www.sciencedirect.com/science/article/pii/S0168165614009341

 

12. Huang L, Xu JH, Yu HL* (2015). Significantly improved thermostability of a reductase CgKR1 from Candida glabata with a key mutation at Asp 138 for enhancing bioreduction of aromatic α-keto esters. Journal of Biotechnology, 203: 54-61.

http://www.sciencedirect.com/science/article/pii/S0168165615001005

 

13. Cao YD, He YC, Li H, Kai GY, Xu JH, Yu HL* (2015). Efficient biosynthesis of rare natural product scopolamine using E. coli cells expressing a S14P/K97A mutant of hyoscyamine 6β-hydroxylase AaH6H. Journal of Biotechnology, 211: 123-129.

http://www.sciencedirect.com/science/article/pii/S0168165615300766

14. He YC*, Tao ZC, Ding Y, Zhang DP, Wu YQ, Lu Y, Liu F, Xue YF, Wang C, Xu JH (2015). Effective biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate by supplementation of L-glutamine, D-xylose and beta-cyclodextrin in n-butyl acetate-water media. Journal of Biotechnology, 203: 62-67.

 http://www.sciencedirect.com/science/article/pii/S0168165615001376 

15. Liu JY, Bian HP, Tang Y, Bai YP, Xu JH* (2015). Double substituted variant of Bacillus amyloliquefaciens esterase with enhanced enantioselectivity and high activity towards 1-(3’,4’-methylenedioxyphenyl)ethyl acetate. Appl. Microbiol. Biotechnol., 99: 1701-1708.

http://link.springer.com/article/10.1007%2Fs00253-014-5992-0

16. Wang RF, Zheng MM, Cao YD, Li H, Li CX, Xu JH*, Wang ZT* (2015). Biotransformation of vina-ginsenoside R7 to rare notoginsenoside ST-4 using a new recombinant glycoside hydrolase from Herpetosiphon aurantiacus. Appl. Microbiol. Biotechnol., 99: 3433-3442.

http://link.springer.com/article/10.1007%2Fs00253-015-6446-z

17. Kong XD, Yu HL, Yang S, Zhou JH, Zeng BB, Xu JH* (2015). Chemoenzymatic synthesis of (R)- and (S)-propranolol using an engineered epoxide hydrolase with a high turnover number. J Mol Catal B: Enzym., 122: 275-281.

http://www.sciencedirect.com/science/article/pii/S1381117715300849

18. Zhang ZJ, Yu HL, Imanaka T, Xu JH* (2015). Efficient production of (R)-(-)-mandelic acid by isopropanol-permeabilized recombinant E. coli cells expressing Alcaligenes sp. Nitrilase. Biochemical Engineering Journal, 95: 71-77.

http://www.sciencedirect.com/science/article/pii/S1369703X14003581

19. Zhang ZJ, Pan J, Ma BD, Xu JH* (2015). Efficient biocatalytic synthesis of chiral chemicals. Adv. Biochem. Eng. Biotechnol. [Epub ahead of print] 2014 Dec 24. DOI 10.1007/10_2014_291

20. Zheng MM, Wang RF, Li CX, Xu JH* (2015). Two-step enzymatic synthesis of ursodeoxycholic acid with a new 7β-hydroxysteroid dehydrogenase from Ruminococcus torques. Process Biochemistry, 50: 598-604.

http://www.sciencedirect.com/science/article/pii/S1359511315000112

 

21. Xu GC, Yu HL*, Shang YP, Xu JH* (2015). Enantioselective bioreductve preparation of chiral halohydrins employing two newly identified stereocomplementary reductases. RSC Advances, 5: 22703-22711. 

http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C4RA16779A

 

22. Yin JG, Xu GC, Zheng GW*, Xu JH* (2015). Cloning and characterization of an enantioselective l-menthyl benzoate hydrolase from Acinetobacter sp. ECU2040. Appl Biochem Biotechnol, 176: 1102-1113.

http://link.springer.com/article/10.1007/s12010-015-1632-0

23. Chen J, Luo XJ, Chen Q, Pan J, Zhou J and Xu JH* (2015). Marked enhancement of Acinetobacter sp. organophosphorus hydrolase activity by a single residue substitution Ile211Ala. Bioresources and Bioprocessing, 2015, 2: 39.

http://www.bioresourcesbioprocessing.com/content/2/1/39

24. Li CX, Jiang XC, Qiu YJ, Xu JH* (2015). Identification of a new thermo- and alkaline-tolerant α-carbonic anhydrase from Lactobacillus delbrueckii: Performance in CO2 biomineralization into vaterite. Bioresources and Bioprocessing 2: 44. doi:10.1186/s40643-015-0074-4

 

25. Zhang YHP, Hu FX, Qian XH, ZJ, Xu YF, Xu JH, Zhang JY, Yong YC. Chemical Biotechnology and Bioengineering, DOI: 10.1039/9781782620129; 03 Jun 2015; ISBN: 978-1-84973-810-1.  Description: In biotechnology and bioengineering, small molecules can be used to increase the efficiency and reduce the cost and damage to the environment of certain bioprocesses. This book introduces readers to the important field of chemically promoted biotechnology and bioengineering and presents the theory behind the biotechnology of enzymatic reactions and how they can be chemically enhanced.

 

 

 

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